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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGCP All Species: 32.42
Human Site: S421 Identified Species: 79.26
UniProt: Q9Y646 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y646 NP_057218.1 472 51888 S421 Q A G V P G A S L L D D L Y K
Chimpanzee Pan troglodytes XP_001146407 472 51991 S421 Q A G V P G A S L L D D L Y K
Rhesus Macaque Macaca mulatta XP_001092016 472 51935 S421 Q A G V P G A S L L D D L Y K
Dog Lupus familis XP_535134 472 52070 S421 Q A G V P G A S L L D D L Y R
Cat Felis silvestris
Mouse Mus musculus Q9WVJ3 470 51795 S419 Q A G V P G A S L R D D L Y K
Rat Rattus norvegicus Q6IRK9 472 52023 S421 Q A G V P G A S L R D D L Y K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505651 259 28465 D212 V P G A S L L D D L K K Y F S
Chicken Gallus gallus XP_418350 469 51964 S419 R D G V P G A S L R D D L S K
Frog Xenopus laevis Q6GQ29 469 51997 S419 Q A G V P G A S L F D D I S K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393631 476 53247 S424 R A G V P G G S L W T Q D D K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 97.6 88.3 N.A. 87.7 87.7 N.A. 44.9 74.1 73 N.A. N.A. N.A. 48.3 N.A. N.A.
Protein Similarity: 100 99.1 98.3 94 N.A. 93.6 92.8 N.A. 49.7 85.8 83.9 N.A. N.A. N.A. 67.6 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 13.3 73.3 80 N.A. N.A. N.A. 53.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 20 80 86.6 N.A. N.A. N.A. 60 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 80 0 10 0 0 80 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 10 10 0 80 80 10 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % F
% Gly: 0 0 100 0 0 90 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 80 % K
% Leu: 0 0 0 0 0 10 10 0 90 50 0 0 70 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 90 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 70 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 20 0 0 0 0 0 0 0 0 30 0 0 0 0 10 % R
% Ser: 0 0 0 0 10 0 0 90 0 0 0 0 0 20 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % T
% Val: 10 0 0 90 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 60 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _